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The mystical concoction inspired many prominent artists and writers – Vincent Van Gogh, Oscar Wilde, Pablo Picasso and Earnest Hemmingway just to list a few (Patocka, Plucar, 2003). Absinthe was said to induce a psychedelic, drug–like state caused by the presence of thujone in the liquor. This toxic chemical brought about the 1915 ban of absinthe, as it was believed to cause brain damage.
Thujone (I), “the most important biologically active compound of absinthe” is found in wormwood, Artemisia absinthium, and has the chemical formula C10H16O (Patocka, Plucar, pg 200). Known also as absinthol, tanacetone and salviol, thujone is a bridged ring containing a ketone group, a methyl group and an iso-propyl group, appearing in the alpha and beta form...
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